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Can cannabinoids help in the treatment of rosacea?

person access_time24. october 2019 chat_bubble_outline0 komentářů remove_red_eye16 shlédnutí
Also called copper rose or fin, rosacea often occurs in adulthood. In the chronic inflammatory skin disease of the face especially the fine vessels of the cheeks, nose, forehead and chin are dilated and the skin is particularly red in these areas. Even the eyes can be affected. However, there are indications that cannabinoids and cannabis seeds can relieve the symptoms of the disease.
 
Rosacea - explained briefly
There are different forms of rosacea. Depending on the severity, various areas of the face are affected by the non-infectious, chronic inflammatory skin disease. Typically, especially the fine veins of the facial skin in the areas of the cheeks, nose, forehead and chin are widened and the facial areas are correspondingly reddened. Other signs may be bumpy pimples. The nose can also change as the disease progresses.
 
Rosacea occurs in adulthood, usually between the ages of 30 and 50 years. Women are more affected than men, but the symptoms are usually more pronounced.
 
Causes of rosacea
About the causes of rosacea can give no final information. Genetic factors seem to play a role in their development, since many sufferers of family members report the same symptoms. A role also seems to play the damage to the facial skin by UV rays. Solar radiation affects the connective tissue as well as blood and lymph vessels and makes a significant contribution to vascular dilation and inflammation.
 
According to recent findings, dermatitis occurs as a result of a defective innate immune response. Factors that favor the symptoms of rosacea include stress, alcohol, sun exposure, warm drinks or spicy foods.
 
The chronic course of the disease requires regular visits to the dermatologist. Care should be taken to avoid the above-mentioned factors that favor the disease. Typically, rosacea is treated with medication. In addition, it is extremely important to protect the affected areas from UV rays.
 
This is where our endocannabinoid system comes into play. Among other things, the receptors of the regulatory system also occur in the skin and play a major role in the protection and regulation of our largest organ.
 
Cannabinoids in the treatment of rosacea
By regulating the endocannabinoid system, cannabinoids can make a significant contribution to alleviating the symptoms of rosacea. The receptors of the regulatory system also occur in the skin and can affect the growth, functionality and balance of skin cells. Scientists have been able to show [1] that cannabinoids have a positive influence on the receptors of the skin and can promote anti-inflammatory or antioxidant properties.
 
Meanwhile, various manufacturers are offering creams and ointments enriched with cannabis or hemp plant ingredients to help treat various inflammatory skin conditions with symptoms similar to rosacea.
 
Clinical trials and laboratory studies [2] have shown that the anti-inflammatory effects of THC and CBD can help relieve redness and irritated skin. In addition, topical application of THC has been shown to reduce symptoms of allergic inflammation.
 
In addition to cannabinoids, hemp seed oil has promising properties that may be of interest for the treatment of rosacea symptoms. Hempseed oil contains unsaturated fatty acids, gamma-linolenic acid and oleic acid, which can reduce the inflammation of the skin. Polyunsaturated fatty acids such as omega-3 and omega-6 can promote blood circulation and provide healthy vessels.
 
After all, stress is considered a major factor that aggravates the symptoms of rosacea. With regular use, CBD can provide more balance and well-being, which could positively affect the course of the disease.
 
Our skin and the endocannabinoid system
Scientists have observed that inflammation of the skin or other irritating stimuli strongly increases the concentration of endocannabinoids anandamide and 2-AG in the skin. It is believed that the body thereby tries to reduce pain and inflammation.
 
In addition, it was observed that pain and inflammation could be alleviated by the suppression of enzymes that degrade endocannabinoids. Through the production of anandamide and 2-AG, our body seems to be trying to circumvent the degradation of endocannabinoids and maintain their effect longer. In addition, the two endocannabinoids influence the development of skin cells. Especially for the epidermis, the uppermost skin layer, the endocannabinoid system seems to play a role with the receptors CB1 and CB2.
 

Source: 

BOEDEFELD, Christian. Können Cannabinoide bei der Behandlung von Rosazea helfen?  17 Feb, 2019. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/koennen-cannabinoide-bei-der-behandlung-von-rosazea-helfen/
 
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