Výsledky vyhledávání v sekci: blog na dotaz dermatitis

Can cannabinoids help in the treatment of rosacea?

access_time24.October 2019 personEditor Testovací

Also called copper rose or fin, rosacea often occurs in adulthood. In the chronic inflammatory skin disease of the face especially the fine vessels of the cheeks, nose, forehead and chin are dilated and the skin is particularly red in these areas. Even the eyes can be affected. However, there are indications that cannabinoids and cannabis seeds can relieve the symptoms of the disease.   Rosacea - explained briefly There are different forms of rosacea. Depending on the severity, various areas of the face are affected by the non-infectious, chronic inflammatory skin disease. Typically, especially the fine veins of the facial skin in the areas of the cheeks, nose, forehead and chin are widened and the facial areas are correspondingly reddened. Other signs may be bumpy pimples. The nose can also change as the disease progresses.   Rosacea occurs in adulthood, usually between the ages of 30 and 50 years. Women are more affected than men, but the symptoms are usually more pronounced.   Causes of rosacea About the causes of rosacea can give no final information. Genetic factors seem to play a role in their development, since many sufferers of family members report the same symptoms. A role also seems to play the damage to the facial skin by UV rays. Solar radiation affects the connective tissue as well as blood and lymph vessels and makes a significant contribution to vascular dilation and inflammation.   According to recent findings, dermatitis occurs as a result of a defective innate immune response. Factors that favor the symptoms of rosacea include stress, alcohol, sun exposure, warm drinks or spicy foods.   The chronic course of the disease requires regular visits to the dermatologist. Care should be taken to avoid the above-mentioned factors that favor the disease. Typically, rosacea is treated with medication. In addition, it is extremely important to protect the affected areas from UV rays.   This is where our endocannabinoid system comes into play. Among other things, the receptors of the regulatory system also occur in the skin and play a major role in the protection and regulation of our largest organ.   Cannabinoids in the treatment of rosacea By regulating the endocannabinoid system, cannabinoids can make a significant contribution to alleviating the symptoms of rosacea. The receptors of the regulatory system also occur in the skin and can affect the growth, functionality and balance of skin cells. Scientists have been able to show [1] that cannabinoids have a positive influence on the receptors of the skin and can promote anti-inflammatory or antioxidant properties.   Meanwhile, various manufacturers are offering creams and ointments enriched with cannabis or hemp plant ingredients to help treat various inflammatory skin conditions with symptoms similar to rosacea.   Clinical trials and laboratory studies [2] have shown that the anti-inflammatory effects of THC and CBD can help relieve redness and irritated skin. In addition, topical application of THC has been shown to reduce symptoms of allergic inflammation.   In addition to cannabinoids, hemp seed oil has promising properties that may be of interest for the treatment of rosacea symptoms. Hempseed oil contains unsaturated fatty acids, gamma-linolenic acid and oleic acid, which can reduce the inflammation of the skin. Polyunsaturated fatty acids such as omega-3 and omega-6 can promote blood circulation and provide healthy vessels.   After all, stress is considered a major factor that aggravates the symptoms of rosacea. With regular use, CBD can provide more balance and well-being, which could positively affect the course of the disease.   Our skin and the endocannabinoid system Scientists have observed that inflammation of the skin or other irritating stimuli strongly increases the concentration of endocannabinoids anandamide and 2-AG in the skin. It is believed that the body thereby tries to reduce pain and inflammation.   In addition, it was observed that pain and inflammation could be alleviated by the suppression of enzymes that degrade endocannabinoids. Through the production of anandamide and 2-AG, our body seems to be trying to circumvent the degradation of endocannabinoids and maintain their effect longer. In addition, the two endocannabinoids influence the development of skin cells. Especially for the epidermis, the uppermost skin layer, the endocannabinoid system seems to play a role with the receptors CB1 and CB2.   Source:  BOEDEFELD, Christian. Können Cannabinoide bei der Behandlung von Rosazea helfen?  17 Feb, 2019. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/koennen-cannabinoide-bei-der-behandlung-von-rosazea-helfen/   source photo: https://pixabay.com/cs/

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CBD gegen Hautkrankheiten - nÃttzt Cannabidiol der Hautgesundheit?

access_time24.October 2019 personEditor Testovací

CBD and skin diseases: Does cannabidiol help with atopic dermatitis? Atopic dermatitis is considered a particularly onerous skin disease, as it often occurs already in infancy. The face and scalp of the baby are already covered shortly after birth with the characteristic milk scab; on the insides of knees and elbows arise so-called flexion eczema. The scaly and weeping eczema on the skin is accompanied by tormenting itching, which robs those affected of their sleep and makes any skin contact - even wearing clothes - painful. In adults, the symptoms usually culminate in spurts, the triggers of which are often not clearly identified.   Atopic dermatitis flare-ups occur when the affected immune system over-reacts to internal or external irritants. The triggers can be both specific foods and stressful situations. The idea of ​​using cannabidiol for the treatment of atopic dermatitis is obvious because the nerve fibers of the skin possess cannabinoid receptors and endocannabinoids have been shown to be involved in the regulation of the immune system.   Cannabinoid ointment relieves eczema symptoms The first attempt to treat atopic dermatitis patients with cannabinoids was undertaken by Munich scientists in 2008. They administered 2456 participants a skin cream with the cannabinoid N-palmitoylethanolamine (PEA). As a result, 60 percent of the subjects were able to reduce itching, redness, and flaking areas of the skin. More than half of the atopic dermatitis patients were also able to do without cortisone medication.    ObCBD as cannabinoid could achieve comparable effects in people with neurodermatitis, has not yet been investigated in clinical trials. Its anti-inflammatory effect, which can suppress excessive immune system responses, has been confirmed in animal studies. On the basis of previous findings, scientists call CBD and cannabidiol containing preparations as a possible future remedy for skin diseases such as eczema, but also acne, contact allergies, psoriasis and itching.    CBD for common skin diseases: Does cannabidiol have an effect on acne? To call acne a skin disease, many people consider exaggerated. In fact, statistically, around 75 to 90 percent of teenagers worldwide suffer from acne-like skin changes. In about 10 percent of those affected, however, this symptom persists in adulthood and causes physical and mental discomfort. In the process, acne does not result from unhealthy diets or poor hygiene - in fact, the pimples and pustules are the result of dysregulation of certain skin cells: both the sebaceous glands and the horn-forming cells appear overactive here. While sebum is increasingly produced, the horny cells close the exits of the sebaceous follicles. The skin fat does not drain, but offers bacteria such as the Propionibacterium acnes a breeding ground and it comes to inflammation.   CBD regulates the activity of certain skin cells At least, laboratory tests suggest that CBD, through the activation of the type 4 vanilloid receptor, reduces both the productivity of the sebaceous cells, as well as the horn-forming activity through other mechanisms Cells (keratinocytes) inhibits. Both effects could have a positive effect on the symptoms of acne. Also in psoriasis, which is also characterized by an overactivity of the horn-forming cells, the regulative action of CBD could possibly be beneficial. However, clinical studies that would confirm a positive effect on acne or psoriasis are still missing at this time.   Cannabidiol for severe skin diseases However, concrete case reports on the effect of CBD on skin diseases are available elsewhere: Epidermolysis bullosa is a serious inherited skin disease that can even lead to death. Those affected suffer from painful wounds, scars and adhesions that limit the range of motion. The symptom picture is sometimes called "butterfly skin" because the epidermis of the patient seems to be as sensitive as the wing of a butterfly.   Could CBD be useful here? An indication can be found in the medical literature. Here is the report of 3 epidermolysis bullosa patients who used CBD oil on the skin. All reported better wound healing, less blistering, and reduced pain from the therapy. One of the patients was even able to do without the opioid painkillers he usually took for the symptoms.    CBD on the skin - does it work in the entire organism? If you use CBD oil or cream, you should be aware that the ingredients are not only local, but also absorbed into the bloodstream. Cannabidiol even reaches the blood 10 times more effectively via the so-called transdermal passage than the psychoactive ingredient THC.    CBD oil or cream - what is best for the application on the skin? While CBD oil is dripped under the tongue, taking cannabidiol through the oral mucosa into the bloodstream, CBD cream and CBD balm develop their effect directly on the skin. Quality products are characterized by the fact that they are based on a full-spectrum extract. In addition to CBD, this contains other cannabinoids, flavonoids and terpenes, and in this way favors the so-called Entourage effect. Scientists assume that different cannabinoids increase each other's beneficial effects.   High-quality CBD creams also contain no artificial preservatives, dyes and fragrances. Only vitamin E, which acts as an effective antioxidant, prevents the cream from spoiling on contact with oxygen. Natural oils and vegetable fats such as shea butter or mango butter additionally help the skin to retain its own moisture and make it supple.   Source:  CBD gegen Hautkrankheiten – nützt Cannabidiol der Hautgesundheit? 1 [online]. 21 Aug,2019, Dostupné z: https://fivebloom.de/blogs/cbd-news/cbd-gegen-hautkrankheiten   source photo: https://pixabay.com/cs/  

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