Notice: Undefined variable: ub in /home/tobo/web/simplycbdoil.org/public_html/application/classes/stalk.php on line 146

Notice: Undefined variable: ub in /home/tobo/web/simplycbdoil.org/public_html/application/classes/stalk.php on line 153

Deprecated: strripos(): Non-string needles will be interpreted as strings in the future. Use an explicit chr() call to preserve the current behavior in /home/tobo/web/simplycbdoil.org/public_html/application/classes/stalk.php on line 153
CANNABINOIDS | simplyCBDoil

Výsledky vyhledávání v sekci: blog na dotaz cannabinoids

What do you know about cannabinodiol?

access_time11.October 2019personEditor Testovací

For how many active ingredients in the cannabis plant, humanity has so far been able to really deal with only a few. Only for a few decades researchers have been researching the plant with scientific methods and trying to fathom its health-promoting properties.For a long time there were not many places in the world where cannabis research was possible from the legal situation. But gradually the individual substances of the hemp plant are examined and their pharmacological properties are scrutinized. Thus, the plant reveals more and more of its many active ingredients.More and more cannabinoids are being researched and have medical benefitsWe already know a lot about tetrahydrocannabinol (THC) and cannabidiol (CBD). And the medical benefits of the cannabinoids cannabigerol (CBG), cannabis romaine (CBC) and cannabinol (CBN), there is already some information. There are also oils especially from CBG, comparable to CBD oil, with which you can do something good for your health. But there are other cannabinoids to discover that can also be of great value to humans, such as cannabinodiol.CBND is made from cannabinolThe phytocannabinoid cannabinoidiol (CBND) is a fully flavored derivative, a variation of CBD. It is sometimes called cannabidinodiol (CBDL). In 1977, it was first isolated by Robert Lousberg. In low concentrations, CBND is found in the flowers of the female cannabis plant. It is produced as a product of the photochemical conversion of cannabinol (CBN), ie by the influence of light. Like tetrahydrocannabinol and cannabinol it has psychotropic properties.The medical benefits of CBNDCannabinodiol is only slowly becoming interesting for medicine. Therefore, little is known about the pharmacological properties of cannabinoid except that it is psychoactive in a similar manner to THC or perhaps tetrahydrocannabivarin. Meanwhile, there is increasing evidence that CBND can be used to treat neuropsychiatric disorders. The compound classified as phytocannabinoid, which is isolated from Lebanese hashish, is said to improve cognitive function in those affected. Whether cannabinodiol will play an even greater role in medical applications in the future will only have to be proven by further investigations. source: GLASMANN, Dieter Klaus. Was weiß man über Cannabinodiol?. 2019, 13 Mai,, 2019. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/was-weiss-man-uber-cannabinodiol/ source photo: https://pixabay.com/cs/

folder_openPřiřazené štítky

Use cannabidiol for cellulite

access_time14.October 2019personEditor Testovací

Our skin is a big and very important organ of the body. It also partially reflects our internal health. That is why the skin is also a topic that the developers of cannabidiol-containing products are concerned about. There are now plenty of CBD creams, ointments and lotions on the market for daily care, for speeding up the healing process of minor injuries or especially for various skin diseases. Of course you can also provide your skin with the helpful cannabinoid by applying the same CBD oil that you also take orally.The health benefits of CBD oilCannabidiol is a natural and largely harmless substance derived from the cannabis plant. This is done by means of different extraction methods. The extract thus produced is added to a carrier oil, usually this is an olive or hemp seed oil. A good extract contains a complete extract of the active ingredients of the cannabis plant. Thus cannabidiol and the other cannabinoids, flavonoids and terpenes can exert all the positive effects on the endocannabinoid system and the whole body for which the plant has long been known: pain relief, reduction of depression and anxiety, protection of nerve cells and much more. In addition to the effects on the internal organs can also cure many skin complaints with CBD oils.What can CBD oil do for cellulite?Cannabidiol is an all-rounder for skin care and the treatment of skin diseases. It can be used against inflammation, itching or for wound healing. It should even support the positive course of treatment of skin cancer. The entourage effect, as the interaction of the cannabis active ingredients is called, is particularly noticeable in the application for the skin. CBD acts as an antioxidant for the skin, it binds free radicals, which promote skin aging, diseases and also cancer. For cellulite, another feature of CBD comes into play. Because it promotes blood flow in the vessels, the whole skin is better supplied with nutrients and pollutants removed.How best to use CBD for the skin?Whether you prefer to use a cannabidiol-containing care product or swears rather on the CBD oil, everyone must decide based on his experience and preferences. In general, the use of CBD oils on the skin also works very well, but this can be quite expensive when applied over a larger area of ​​skin. Therefore, the topical use of a CBD oil is particularly suitable for the treatment of small wounds or irritated skin. For general care, CBD beauty products are best. The CBD oil does not have to be set aside for that. Because applied internally, so ingested, cannabidiol works everywhere in the body, thus in the skin cells. Source: GLASMANN, Dieter Klaus Glasmann. Cannabidiol bei Cellulite einsetzen, 26 Apr, 2019. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/cbd-in-der-medizin/cannabidiol-bei-cellulite-einsetzen/source photo: https://pixabay.com/cs/ 

folder_openPřiřazené štítky

Can cannabinoids help in the treatment of rosacea?

access_time24.October 2019personEditor Testovací

Also called copper rose or fin, rosacea often occurs in adulthood. In the chronic inflammatory skin disease of the face especially the fine vessels of the cheeks, nose, forehead and chin are dilated and the skin is particularly red in these areas. Even the eyes can be affected. However, there are indications that cannabinoids and cannabis seeds can relieve the symptoms of the disease. Rosacea - explained brieflyThere are different forms of rosacea. Depending on the severity, various areas of the face are affected by the non-infectious, chronic inflammatory skin disease. Typically, especially the fine veins of the facial skin in the areas of the cheeks, nose, forehead and chin are widened and the facial areas are correspondingly reddened. Other signs may be bumpy pimples. The nose can also change as the disease progresses. Rosacea occurs in adulthood, usually between the ages of 30 and 50 years. Women are more affected than men, but the symptoms are usually more pronounced. Causes of rosaceaAbout the causes of rosacea can give no final information. Genetic factors seem to play a role in their development, since many sufferers of family members report the same symptoms. A role also seems to play the damage to the facial skin by UV rays. Solar radiation affects the connective tissue as well as blood and lymph vessels and makes a significant contribution to vascular dilation and inflammation. According to recent findings, dermatitis occurs as a result of a defective innate immune response. Factors that favor the symptoms of rosacea include stress, alcohol, sun exposure, warm drinks or spicy foods. The chronic course of the disease requires regular visits to the dermatologist. Care should be taken to avoid the above-mentioned factors that favor the disease. Typically, rosacea is treated with medication. In addition, it is extremely important to protect the affected areas from UV rays. This is where our endocannabinoid system comes into play. Among other things, the receptors of the regulatory system also occur in the skin and play a major role in the protection and regulation of our largest organ. Cannabinoids in the treatment of rosaceaBy regulating the endocannabinoid system, cannabinoids can make a significant contribution to alleviating the symptoms of rosacea. The receptors of the regulatory system also occur in the skin and can affect the growth, functionality and balance of skin cells. Scientists have been able to show [1] that cannabinoids have a positive influence on the receptors of the skin and can promote anti-inflammatory or antioxidant properties. Meanwhile, various manufacturers are offering creams and ointments enriched with cannabis or hemp plant ingredients to help treat various inflammatory skin conditions with symptoms similar to rosacea. Clinical trials and laboratory studies [2] have shown that the anti-inflammatory effects of THC and CBD can help relieve redness and irritated skin. In addition, topical application of THC has been shown to reduce symptoms of allergic inflammation. In addition to cannabinoids, hemp seed oil has promising properties that may be of interest for the treatment of rosacea symptoms. Hempseed oil contains unsaturated fatty acids, gamma-linolenic acid and oleic acid, which can reduce the inflammation of the skin. Polyunsaturated fatty acids such as omega-3 and omega-6 can promote blood circulation and provide healthy vessels. After all, stress is considered a major factor that aggravates the symptoms of rosacea. With regular use, CBD can provide more balance and well-being, which could positively affect the course of the disease. Our skin and the endocannabinoid systemScientists have observed that inflammation of the skin or other irritating stimuli strongly increases the concentration of endocannabinoids anandamide and 2-AG in the skin. It is believed that the body thereby tries to reduce pain and inflammation. In addition, it was observed that pain and inflammation could be alleviated by the suppression of enzymes that degrade endocannabinoids. Through the production of anandamide and 2-AG, our body seems to be trying to circumvent the degradation of endocannabinoids and maintain their effect longer. In addition, the two endocannabinoids influence the development of skin cells. Especially for the epidermis, the uppermost skin layer, the endocannabinoid system seems to play a role with the receptors CB1 and CB2. Source: BOEDEFELD, Christian. Können Cannabinoide bei der Behandlung von Rosazea helfen?  17 Feb, 2019. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/koennen-cannabinoide-bei-der-behandlung-von-rosazea-helfen/ source photo: https://pixabay.com/cs/

folder_openPřiřazené štítky

The anti-oxidative properties of CBD

access_time24.October 2019personEditor Testovací

Many nutrition experts and counselors point out how important antioxidants are to our health and well-being. But what exactly is behind these substances? What qualities do they possess and how can our bodies benefit from them? Simply put, antioxidants are substances that inhibit oxidation and reduce the associated so-called oxidative stress. During oxidation, waste products are formed in our body and free radicals are formed. The body's own antioxidants, such as glutathione, are usually insufficient to prevent the production of free radicals. This is especially the case with increasing age, as the oxidative stress increases with increasing age. That is why it is important to supply the body with antioxidants from the diet. Actually, oxygen is associated with life. That's true, of course, but in this case our body produces the already mentioned free radicals by oxidation of other substances (reaction with oxygen). From them, a kind of chain reaction can occur in which molecules, cells or tissue can be damaged or irreparably destroyed. By reacting with them, antioxidants protect against free radicals. CBD as an antioxidantFor a long time, vitamins such as C and E were among the most powerful antioxidants. In terms of mode of action, cannabidiol does not really differ from an antioxidant. The chemical structure of the cannabinoid contains an oxygen atom that can be released to free radicals and thus neutralizes them. This free oxygen compound is responsible for the antioxidant effects of CBD. Several studies even confirm that the cannabinoids THC and CBD have a significant neuroprotective effect as antioxidants, which is many times stronger than for vitamins C and E. ConclusionAntioxidants are extremely important to our body. Without them, free radicals can cause immense damage. By providing oxygen atoms, antioxidants can neutralize the harmful compounds, making a vital contribution to our health. In addition to vitamins C and E, cannabidiol has become a good source of antioxidants. Although more research is needed in this area, the results obtained to date are quite promising and provide insight into the antioxidant potential of CBD. In addition, CBD could also keep neurodegenerative diseases such as Parkinson's or Alzheimer's at bay. The potential of cannabinoid is huge. Unfortunately, it is difficult to make general statements and the effectiveness of CBD is best tested by yourself. Every organism responds differently and should be slowly accustomed to using CBD as a nutritional supplement. Although no serious side effects of CBD are known, consult a doctor if you have any concerns about taking it. Source: BOEDEFELD, Christian. Die antodioxidativen Eigenschaften von CBD. 1 [online].19 Dec, 2019. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/cbd-in-der-medizin/die-antodioxidativen-eigenschaften-von-cbd/ source photo: https://pixabay.com/cs/  

folder_openPřiřazené štítky

CBD - protective effect for the cardiovascular system

access_time24.October 2019personEditor Testovací

First place among the leading causes of death worldwide is cardiovascular disease, which is due to inflammation of the cardiovascular system. A good means of prevention could be the cannabinoid CBD (cannabidiol) known for its anti-inflammatory effect. Animal experiments also suggest that CBD can also help to recover better and faster from the consequences of a heart attack or stroke. Although one can counteract such diseases through a healthy lifestyle, unfortunately, most people only become aware of the dangers when the first symptoms have already appeared. Often, however, it is no longer enough to "just" get rid of bad habits, but further measures will be necessary. All by itself or in combination with conventional medical treatments, cannabis or cannabidiol could be a good way to strengthen and protect the cardiovascular system. The heart and its associated network of blood vessels, known as the cardiovascular system, acts as a body-wide transport system for our blood. If this system has an error or corruption, it can have serious consequences. On the one hand, this can trigger a heart attack, which leads to the death of one area of ​​the heart muscle (myocardium), on the other hand, a stroke can be the result, which means that the brain cells can no longer be adequately supplied. Often, such a disease can be attributed to inflammation in the organism. And this is the starting point for treatment with CBD, whose anti-inflammatory properties have been proven in various scientific studies. In one of these studies, created by an international team of researchers from Israel, Taiwan, Hungary, the USA and Switzerland, animal experiments have shown that cannabidiol can help to heal myocarditis. CD3 and CD4 lymphocyte counts decreased significantly in rats treated with CBD on a sustained basis. This could counteract an expansion of heart disease, giving the damaged tissue after a heart attack the opportunity to recover faster and more sustainably. In another study, in which rabbits were treated with CBD after a heart attack, a positive influence on the healing process could be confirmed, unlike in the placebo group. But also to prevent such a cardiovascular disease, the use of CBD may be useful to eliminate potential risk factors. In addition to the well-known sedative and stress-reducing effect, positive effects on blood pressure, metabolism and obesity could also be observed in further studies. Furthermore, American scientists have recently completed an evaluation of 24 studies conducted between 1975 and 2017 on the "link between cannabis and cardiovascular disease" and concluded that there was no clear evidence of a link between cannabis use and the triggering of heart (muscle) infarctions or strokes. In addition to the ones mentioned here, there are a lot of other studies that confirm the positive medical benefit of cannabidiol on cardiovascular disease. In addition to cannabidiol, cannabis also contains a variety of other cannabinoids. The best-known and most researched of these is probably tetrahydrocannabinol (THC). THC is often warned that it is harmful to the heart and the rest of the cardiovascular system. As so often, however, it depends on the dosage. THC, just like CBD, can activate the CB2 receptors, which are located above all in the immune cells of our body. Therefore, it also has the ability to reduce inflammation and the level of free radicals that may otherwise increase the risk of strokes or heart attacks. THC, however, also docks to the CB1 receptors in the body. These are found, inter alia, throughout the cardiovascular system, where they are everywhere from the blood vessels to the heart muscle to the nerves in the brain responsible for heart rate control. On the one hand, activation of these receptors may be positive, e.g. On the other hand, however, with high doses of THC, the interaction between the cannabinoid and the CB1 receptors may superimpose the effect of the CB2 receptors and produce the exact opposite effect. In addition, activation of the CB1 receptors may contribute to the formation of deposits of substances such as cholesterol and fat in the blood vessels. Should one therefore be faced with the decision to choose a variety that is as supportive as possible to the protection and function of the cardiovascular system, then it might be worth taking a look at the low THC / high CBD category. Source: KRONBERGER, Ferdinand. CBD – schützende Wirkung für das Herz-Kreislauf-System. 1 [online]. 19 Dec, 2019. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/cbd-in-der-medizin/cbd-schuetzende-wirkung-fuer-das-herz-kreislauf-system/ source photo: https://pixabay.com/cs/ 

folder_openPřiřazené štítky

How does CBD work? - An overview

access_time24.October 2019personEditor Testovací

Cannabidiol is a versatile drug with a wide range of uses. CBD is a non-psychoactive cannabinoid. This means that it has no intoxicating effect on our central nervous system and does not affect our perception. CBD has a calming effect and can help fight inflammation, pain, cramps, anxiety, nausea and general wellbeing. Somehow or other, the effect of CBD is often described. The effect is mainly due to the activation of our cannabinoid receptors, CB1 and CB2. Today it is proven that cannabinoids have a therapeutic benefit in various diseases. Nonetheless, the question of the actual effect of CBD often crops up. How does CBD actually work? CBD is analgesicThe analgesic effect of cannabidiol has been demonstrated in numerous studies. By activating certain receptors, CBD influences pain perception. The spectrum of impact is very versatile. CBD can help with pain caused by an inflammatory condition such as arthritis. In addition, the cannabinoid is able to inhibit chronic pain, migraine or menstrual cramps. CBD is anti-inflammatoryCannabidiol can reduce acute and chronic inflammation in the body. For this reason, CBD is also often used to treat inflammation of the gastrointestinal tract, in asthma or arthritis. Also, for chronic inflammatory skin diseases such as psoriasis, the topical application of CBD may be helpful. CBD is anorexicCannabinoid CBD reduces appetite and can help you lose weight. The appetite-suppressing effect is also interesting in the context of a conscious lifestyle. This mechanism of action is due to the blockade of a specific receptor of our endocannabinoid system and is used, for example, to treat obesity. CBD is antiemeticThe effect against nausea and nausea is interesting in many ways. Not only is CBD a perfect traveling companion to help against travel sickness, it can also reduce the nausea associated with chemotherapy. As with the anorectic effect of CBD, cannabinoid receptors of our endocannabinoid system play a crucial role. CBD is anti-kineticSeveral clinical studies provide evidence for the sedative effect of CBD on the gastrointestinal tract. A disturbed digestive system can decisively affect our well-being. Not to forget that the gut plays a crucial role in our immune system and general well-being. CBD has an anxiolytic effectCBD can relieve anxiety and the symptoms it causes. CBD binds to adenosine and serotonin receptors in the spinal cord, which are activated by drugs in mental illness. Including depression and anxiety. The anxiety-calming and soothing effect can help to look at situations from a different angle and reassess them. CBD is neurolepticCBD affects the nervous system and has been shown to reduce the loss of reality, hallucinations and delusions. CBD is antiepilepticThe effective effect of epilepsy has been confirmed in some studies, many of which benefit. In conjunction with other antiepileptic therapies, seizure frequency has been reduced in patients with previously refractory epilepsy forms. CBD is antispasmodicCramping and tension can be resolved by CBD. Especially in MS-induced spasticity the cannabidiol shows a promising effect. CBD is anti-insomniacAs it turns out, the active ingredient CBD also seems to serve as a sleep aid. Many users report a significant improvement in sleep when taking CBD on a regular basis. This is not least because of the calming effect. It can make it easier to fall asleep and sleep through the night. CBD is immunosuppressiveCB2 receptors affect our immune system and are involved in a variety of functions such as immunosuppression. So far, there are only animal studies, but these show an effective effect of CBD in allergies and hypersensitivity. CBD is anti-diabeticScientists suggest that CBD could prevent diabetes and reduce consequences. Inflammation of the pancreas in type 1 diabetes affects insulin production. Due to the anti-inflammatory effect CBD can be used there. Due to its additional effect on circulatory disorders, CBD is also of interest in type 2 diabetes. CBD is neuroprotectiveA WHO report on the effects of CBD also mentions the neuroprotective effect.  ConclusionThe endoannabinoid system of the human body consists of a network of receptors that are distributed throughout our body and not infrequently, an imbalance of this system is responsible for complaints. Cannabidiol can restore homeostasis. The primary receptors CB1 and CB2 are transmitters and receivers of messenger substances and can be activated and stimulated by cannabinoids. While the CB1 receptor is responsible for controlling the nervous system, the CB2 receptor affects our immune system. The spectrum of action of CBD is huge. In any case, it should be noted that substances vary from person to person and that general statements on dosage and effects are difficult. Important is the regular intake of CBD. It is best integrated into everyday life as a dietary supplement in order to best benefit from the medical potential of cannabinoids. Source: BOEDEFELD, Christian. Wie wirkt CBD? – Eine Übersicht.28 Sep, 2019,. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/cbd-in-der-medizin/wie-wirkt-cbd-eine-uebersicht/ source photo: https://pixabay.com/cs/ 

folder_openPřiřazené štítky

POSSIBILITIES AND EFFECT OF CBD IN REGULAR PAIN

access_time24.October 2019personEditor Testovací

Many girls and women suffer from severe discomfort during their days. Abdominal cramps, headaches and general malaise are not uncommon. Sometimes the symptoms are so severe that it is difficult to cope with everyday life. Cannabidiol, also called CBD, has been used for millennia as an effective remedy for menstrual problems. CBD for menstrual pain you can take in different ways and thereby provide relief for menstrual problems. THE CAUSE OF REGULAR PAINTo understand why women and girls often suffer from menstrual cramps and why CBD can help against menstrual pain, we first need to look closely at the processes in the female body. In the course of the female cycle, which lasts for an average of 28 days, the uterus forms a heavily perfused and thick mucous membrane. If you became pregnant, this layer of mucus would serve as a breeding ground for the fertilized egg to keep it safe. However, if there is no fertilization, the body repels this mucous membrane again. This mucous layer is thus eliminated with your period. For this process to happen, the muscles in the uterus work and create contractions. The previously heavily perfused tissue is then less supplied with blood. It comes to menstrual cramps. These cramps are perceived differently by every woman. For some, this pain can be very strong - to the point of unbearable - fail. CBD for menstrual pain is now used by many women to relieve the symptoms of menstrual cramps. Why? You will find out here. CBD IN USE FOR MILLIONSAccording to cannabinoid researchers, the beneficial effects of hemp have been known since antiquity, especially in gynecology. However, the first written document comes only from the 11th century. In an Old English herbarium hemp is recommended as a remedy for painful breasts. Fleetwood Churchill, an English physician, writer and obstetrician, first recommended cannabis for use in the cervical area in 1849. Indian hemp has also been used to stimulate and improve uterine contractions at birth. Against regular pain, the mode of action of this Indian hemp was repeatedly used and proven. Especially the pain-relieving and pain-preventing effect of hemp has been highlighted in many gynecology and obstetrics textbooks, such as those by Grailey Hewitt. Likewise, a whole collection of studies dealing with hemp against gynecology led Dr. Russo, recommending the use of hemp with feverfew. This combination should be taken before and during the period to relieve symptoms. The fact is that the analgesic effect of cannabidiol has been known for 4,000 years. HOW CBD WORKSThere are natural cannabinoids in every human organism. These fulfill the function of messenger substances, which take over the communication between the cells in the nervous system. If you use CBD as a medicine, the drug will affect these endocannabinoids. Because the molecules of CBD adhere to those receptors that are responsible for the transmission of pain signals. These are blocked so that the sensation of pain is reduced. The result is the relaxation of the muscles and the natural release of cramps. In this way, the painful symptoms of menstruation are alleviated and the well-being increased. Incidentally, according to the current state of research, no side effects of CBD have yet been detected. HOW YOU CAN TAKE CBD AGAINST REGULAR PAINTo take CBD for menstrual problems, you have different options to choose from. On the one hand, there is the CBD oil that you just dribble under the tongue. Furthermore, there are capsules that contain crystalline CBD or preparations that act by massaging the lower part of the abdomen. However, pay special attention to the dosage in order to obtain the desired effect. INJECTION AND DOSE OF CBD OILCBD oil you get in different concentrations. For beginners are 5 percent in the oil. But there are also oils with a CBD content of up to 25 percent. In most cases, the vials are equipped with a pipette, with which you easily drip the oil on or under the tongue. In this way, the active ingredient of CBD gets directly into your body. After a quarter to half an hour, the effect unfolds completely. CBD oil is best used in the morning and in the evening. If necessary, you can also often resort to the oil. THE RIGHT DOSAGE OF CBD CAPSULESAlso in capsule form you get CBD in different concentrations. Unlike the oil, the effect of the CBD Ka occurs  Source: MÖGLICHKEITEN UND WIRKUNG VON CBD BEI REGELSCHMERZEN. 1 [online]. 16 Oct, 2019. Dostupné z: https://hanf-im-glueck.shop/cbd-gegen-regelschmerzen/ source photo: https://pixabay.com/cs/

folder_openPřiřazené štítky

GPR55 - The new cannabinoid receptor

access_time24.October 2019personEditor Testovací

His discovery is actually almost 20 years back, but only today he gains attention and importance. Meanwhile, the receptor called GPR55 also becomes CB3, the third relevant cannabinoid receptor in the human endogenous cannabinoid system. Endocannabinoid systemUntil quite some time ago, we knew that THC, which resembles the endogenous cannabinoid anandamide, binds to receptors in the brain, and as a result has an effect on our body. In the meantime, we know about the endocannabinoid system, which allows humans to use endocannabinoids, which the body itself produces, to perform a variety of health and immune functions. This system also harnesses the cannabinoids that we infuse from the outside by taking cannabis. The CB1 receptorSo far, two receptors are known, which are simply described with CB1 and CB2. The CB1 receptor can bind to both THC and CBD. Because they "compete" for the CB1 receptor during the effect of cannabis in the body, and CBD is not known to be psychoactive, CBD cushions the "high" effect of THC. These receptors are found mainly in the central nervous system, thus affecting the sensation of pain and also the motor skills, but also emotions, memory and appetite. The CB2 receptorThe CB2 receptor is found in organs of the immune system, mast cells and lymphocytes. While cannabis is believed to affect the immune system, the assumption that CBD interacts directly with the CB2 receptor is outdated. Rather, it seems that the cannabinoids cause the body to use more of its own endocannabinoids. CBD, GPR55 and cancerThe receptor GPR55, which was discovered in 1999 and can be found in the brain and peripheral nervous system, seems to be able to work with many different cannabinoids. It has differences to CB1 and CB2, but is 13 percent identical in construction to CB1 and 14.4 percent to CB2. One might now assume that cannabidiol (CBD) might dock specifically to the CB3 receptor. However, this does not seem to be the case, CBD even blocks the receptor. But this does not mean that CBD is useless for the receptor or for the medical influence of it, on the contrary. GPR55 signaling is said to be associated with the development or progression of cancer. Thus, the use of CBD targeted to block the signal transmission inhibit the growth of some tumors. CBD, GPR55 and epilepsyAlthough the diseases do not resemble each other, the apparent effect of CBD in epilepsy can be explained by the same principle as cancer. Among other things, GPR55 also occur in the hippocampus, the area of ​​the brain in which spatial orientation and long-term memory are located. CBD has shown significant improvements in the intensity, quantity, and duration of seizures in some forms of epilepsy. CBD, GPR55 and irritable bowel syndromeCBD also has a positive influence on this intestinal disease. Fast and permanent improvement of well-being and relief of symptoms is reported. And again, this is associated with inhibition of signal transduction from GPR55. But in irritable bowel syndrome, it is also the anti-inflammatory properties of CBD, the help in the most chronic stomach and intestinal disorders. Only the beginningMany details about the CB3 receptor and the role it plays in our health are still unclear. But this concerns the whole endogenous cannabinoid system and its receptors, the cannabinoids, whether endogenous or supplied, and the terpenes and their many interactions and possible interactions with our bodies. But with every new insight, the accuracy with which we can use the properties of the cannabis plant for our health increases. Source: KLAUS GLASMANN, Dieter. GPR55 – Der neue Cannabinoid-Rezeptor. 1 [online] 30 Aug, 2019. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/gpr55-der-neue-cannabinoid-rezeptor/ source photo: https://pixabay.com/cs/

folder_openPřiřazené štítky

CBD against circulatory disorders

access_time24.October 2019personEditor Testovací

A number of problems an organism can develop in the course of a lifetime are associated with impaired blood flow and inadequate oxygenation of body parts and organs. These include minor cramping of the muscles in the extremities as well as stroke, in which areas of the brain are underserved and long-term brain damage can remain. Disturbed blood flowBlood flows through every part of our body, only dead cells such as hair and fingernails are not traversed by vessels that transport all imaginable nutrients to the smallest angles. Since our diet and our lifestyle also pollutants, fats and the like can enter our bloodstream, the blood flow in many parts of the body can be disturbed by deposits. In addition, with aging, the flexibility of our veins subsides, but also environmental influences and harmful habits like smoking can constrict the vessels. Small tingling and big risksRegardless of the causes of a circulatory disorder or where it is located, it is commonly referred to as ischemia (low blood flow). In the arms or legs show slight circulatory problems, in which the foot or leg begin to tingle, also cramps of the muscles are possible. The death of parts of the body, for example the well-known smoker's leg, can also be the result of a circulatory disorder. In even worse cases, ischemia threatens the heart or brain, and can lead to strokes and heart attacks, and thus become life threatening. Canes for ischemia?The fact that smoking is harmful, narrows the blood vessels and takes away their flexibility, many potheads regret, after all, it remains to this day, the most popular form of cannabis. On the other hand, the example of glaucoma, which is related to the intraocular pressure and blood flow of the eye, has long been proven that cannabis can improve hemodynamics, ie blood flow. Cannabidiol (CBD) has several effects on blood circulation. Both the soothing, relaxing effect that lowers blood pressure and the vasodilation effect may be important here. In the genesis of ischemic strokes, remarkable results have already been achieved through the use of CBD. In admittedly unsightly tests on rats, CBD has been able to minimize brain damage by 17 percent. CBD inhibits arteriosclerosisArterial calcification and deposits in the blood vessels are one of the main causes of ischemic diseases. Here cannabidiol is medically particularly interesting. Research from Switzerland now assumes that CBD can slow down the progression of arteriosclerosis caused by high blood sugar levels. This prevents ischemic diseases or influences existing ones positively. Since smoking cannabis (especially mixed with tobacco), even if it is a high CBD variety, is rather counterproductive, CBD oils and extracts, which are available as a dietary supplement, are suitable. What to look forOf course, if you suffer from a serious circulatory disorder, going to the doctor is not only compulsory but also the only sensible thing to do. The risks are too big here to carry out self-experiments. But of course you can certainly discuss the use of CBD products with the doctor. When choosing the product one should always keep in mind the entourage effect, according to which the effects of cannabinoids and terpenes favor and enhance one another. This also makes sense for ischemic symptoms, as the cannabinoid cannabigerol (CBG), for example, has an effect on blood pressure. It is therefore advisable to always use CBD products with the full spectrum of cannabis, ie full-spectrum CBD oils or full extracts. Manufacturers who work with rich raw materials and deliver quality will surely mark this on their labels. If only CBD is indicated on the packaging of an oil, and the oil may still be colorless, it can not necessarily be assumed that it contains an extract of all the active ingredients of the hemp plant. Source: KLAUS GLASMANN, Dieter. CBD gegen Durchblutungsstörungen. 1 [online], 30 Sep, 2019. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/cbd-in-der-medizin/cbd-gegen-durchblutungsstoerungen/ source photo: https://pixabay.com/cs/

folder_openPřiřazené štítky

CBD Oil - What can the miracle cure?

access_time24.October 2019personEditor Testovací

CBD oil is the abbreviation for cannabidiol oil. This is a hemp extract oil - without intoxicating effect. However, you can use the oil to relieve health problems. Because the hemp extract oil has an analgesic effect and balances the moods of the psyche. Hemp extract is obtained from the hemp flower. These plants hardly contain tetrahydrocannabinol (THC) because CBD oil must not contain THC. Otherwise it is under the Narcotics Act. Therefore, CBD oil is made from hemp plants that contain a lot of cannabidiol. The compositionBy adding a base oil, hemp extract oil also contains hempseed oil. Cannabidiol, flavonoids and more than 50 substances of cannabinoids are detectable in the hemp extract. It contains no substances that are responsible for a noise effect. Relieve discomfortYou can use CBD oil to relieve many ailments. Unfortunately, we can not make any medically relevant promises in connection with CBD because of the current legal situation.As there are always new positive news from medicine and research and a number of studies indicate the positive effects, you can find many interesting articles on the net.The application CBD oil can be used both externally and internally. Please always follow the recommendation of the manufacturer, if you intend to take the oil internally. So the drops are given in the morning and evening under the tongue. From experience, it makes sense to start with a small amount first. So you can watch how you get the drops. Then you can increase the amount slowly. The exact number of drops depends on the compatibility. Therefore, you should always find out for yourself which dose helps you. side effectsIn general, CBD oil is well tolerated. Nevertheless, it is possible that you notice side effects. It can be fatigue, nausea or diarrhea. Where the signs such as more or less hungry are not clearly attributable to the drop. These effects also change the weight. You should ask a doctor if you can use the oil if you regularly take other medicines. Because even here, the effect of the drugs can be influenced. If you use the oil to rub the skin with it, then you can do a test before. If there is no change in the treated area then you can apply the oil. Since there are not enough studies with the oil, pregnant women and children should not use CBD oil. This also applies to the intake of the drops, because it is not known exactly how the oil in children affects the development and health. ConclusionYou can relieve or alleviate many health problems with CBD oil. If you want to buy the drops, then look for a good quality and best without THC. The drops are not prescription. You can buy the product yourself. You take no drugs with CBD Oil and you will not get intoxicated if you use CBD Oil. So you can not depend on the drops. Serious side effects are not known, however, a slight intolerance may occur. Taking hemp as a remedy is not new. The positive effect has been known for a long time. CBD oil is a real wonder drug. In many cases the effect has been proven in studies. The research is still not so far that there is the product as a drug. Source: CBD Öl - Was kann das Wundermittel? 12 Jul, 2018. Dostupné z: https://www.mrs-hanf.de/2018/07/12/cbd-%C3%B6l-was-kann-das-wundermittel/ source photo: https://pixabay.com/cs/

folder_openPřiřazené štítky

CBD gegen Hautkrankheiten - nÃttzt Cannabidiol der Hautgesundheit?

access_time24.October 2019personEditor Testovací

CBD and skin diseases: Does cannabidiol help with atopic dermatitis?Atopic dermatitis is considered a particularly onerous skin disease, as it often occurs already in infancy. The face and scalp of the baby are already covered shortly after birth with the characteristic milk scab; on the insides of knees and elbows arise so-called flexion eczema. The scaly and weeping eczema on the skin is accompanied by tormenting itching, which robs those affected of their sleep and makes any skin contact - even wearing clothes - painful. In adults, the symptoms usually culminate in spurts, the triggers of which are often not clearly identified. Atopic dermatitis flare-ups occur when the affected immune system over-reacts to internal or external irritants. The triggers can be both specific foods and stressful situations. The idea of ​​using cannabidiol for the treatment of atopic dermatitis is obvious because the nerve fibers of the skin possess cannabinoid receptors and endocannabinoids have been shown to be involved in the regulation of the immune system. Cannabinoid ointment relieves eczema symptomsThe first attempt to treat atopic dermatitis patients with cannabinoids was undertaken by Munich scientists in 2008. They administered 2456 participants a skin cream with the cannabinoid N-palmitoylethanolamine (PEA). As a result, 60 percent of the subjects were able to reduce itching, redness, and flaking areas of the skin. More than half of the atopic dermatitis patients were also able to do without cortisone medication.  ObCBD as cannabinoid could achieve comparable effects in people with neurodermatitis, has not yet been investigated in clinical trials. Its anti-inflammatory effect, which can suppress excessive immune system responses, has been confirmed in animal studies. On the basis of previous findings, scientists call CBD and cannabidiol containing preparations as a possible future remedy for skin diseases such as eczema, but also acne, contact allergies, psoriasis and itching.  CBD for common skin diseases: Does cannabidiol have an effect on acne?To call acne a skin disease, many people consider exaggerated. In fact, statistically, around 75 to 90 percent of teenagers worldwide suffer from acne-like skin changes. In about 10 percent of those affected, however, this symptom persists in adulthood and causes physical and mental discomfort. In the process, acne does not result from unhealthy diets or poor hygiene - in fact, the pimples and pustules are the result of dysregulation of certain skin cells: both the sebaceous glands and the horn-forming cells appear overactive here. While sebum is increasingly produced, the horny cells close the exits of the sebaceous follicles. The skin fat does not drain, but offers bacteria such as the Propionibacterium acnes a breeding ground and it comes to inflammation. CBD regulates the activity of certain skin cellsAt least, laboratory tests suggest that CBD, through the activation of the type 4 vanilloid receptor, reduces both the productivity of the sebaceous cells, as well as the horn-forming activity through other mechanisms Cells (keratinocytes) inhibits. Both effects could have a positive effect on the symptoms of acne. Also in psoriasis, which is also characterized by an overactivity of the horn-forming cells, the regulative action of CBD could possibly be beneficial. However, clinical studies that would confirm a positive effect on acne or psoriasis are still missing at this time. Cannabidiol for severe skin diseasesHowever, concrete case reports on the effect of CBD on skin diseases are available elsewhere: Epidermolysis bullosa is a serious inherited skin disease that can even lead to death. Those affected suffer from painful wounds, scars and adhesions that limit the range of motion. The symptom picture is sometimes called "butterfly skin" because the epidermis of the patient seems to be as sensitive as the wing of a butterfly. Could CBD be useful here? An indication can be found in the medical literature. Here is the report of 3 epidermolysis bullosa patients who used CBD oil on the skin. All reported better wound healing, less blistering, and reduced pain from the therapy. One of the patients was even able to do without the opioid painkillers he usually took for the symptoms.  CBD on the skin - does it work in the entire organism?If you use CBD oil or cream, you should be aware that the ingredients are not only local, but also absorbed into the bloodstream. Cannabidiol even reaches the blood 10 times more effectively via the so-called transdermal passage than the psychoactive ingredient THC.  CBD oil or cream - what is best for the application on the skin?While CBD oil is dripped under the tongue, taking cannabidiol through the oral mucosa into the bloodstream, CBD cream and CBD balm develop their effect directly on the skin. Quality products are characterized by the fact that they are based on a full-spectrum extract. In addition to CBD, this contains other cannabinoids, flavonoids and terpenes, and in this way favors the so-called Entourage effect. Scientists assume that different cannabinoids increase each other's beneficial effects. High-quality CBD creams also contain no artificial preservatives, dyes and fragrances. Only vitamin E, which acts as an effective antioxidant, prevents the cream from spoiling on contact with oxygen. Natural oils and vegetable fats such as shea butter or mango butter additionally help the skin to retain its own moisture and make it supple. Source: CBD gegen Hautkrankheiten – nützt Cannabidiol der Hautgesundheit? 1 [online]. 21 Aug,2019, Dostupné z: https://fivebloom.de/blogs/cbd-news/cbd-gegen-hautkrankheiten source photo: https://pixabay.com/cs/ 

folder_openPřiřazené štítky

Is CBD suitable for children?

access_time24.October 2019personEditor Testovací

Cannabis contains many pharmacologically interesting properties, which are primarily responsible for two groups of substances, cannabinoids and terpenes. Among the cannabinoids, Δ9-trans-tetrahydrocannabinol, THC for short, has been of particular interest over the last decades, especially in the area of ​​consumption. Only a few years ago, a second cannabinoid has been recognized by science and the public, making it the most interesting agent of hemp for many people today, especially for those who do not want it intoxicating. Of course we are talking about cannabidiol (CBD), a molecular compound that can have a lot of medicinal functions without the psychoactive effects that THC has. Cannabidiol is harmless and healthy at the same timeSince CBD has proven to be very useful and harmless, legal cannabinoid has made it into a variety of health-promoting agents for external and internal use. Whether for consumption in food or dietary supplements, or even applied to the skin by ointments, tinctures or creams, CBD has become the trend of the health and wellness industry. In addition, it remains interesting for medical research and practice. Epilepsy, sleep disorders, anxiety disorders, ADHD and many other diseases can be treated successfully with cannabidiol. The contradictory treatment of CBDSome of the conditions for which CBD promises relief, such as epilepsy and ADHD, affect children in particular. Entering specialty stores whose product ranges are CBD cannabis products, however, may generally be entered only from the age of 18 years. Thus, it is quite understandable that some people are unsure about whether CBD can cause harm to children. If it is not psychoactive and harmless, can it then be administered to a child on a private basis, so that it also benefits from the health benefits? Do you have to hide your CBD products from your children, or can you keep them accessible to them? How compatible is the safety of cannabidiol with the age restrictions that CBD shops are subject to? Cannabidiol in public and legal perceptionTo understand these circumstances, one has to take a closer look at several factors. The legal situation that exists for CBD is due to the fact that cannabidiol is still an active ingredient derived from cannabis. This and the THC content which is often present in CBD products, even if in very low concentrations, justify the age restrictions for CBD shops. Of course, the fact that they mostly sell smokers and smokers in addition to CBD oils and Co. is also a good reason not to let minors into the shops. Thus, the legal position for CBD could change in parts insofar as an assortment includes only products with no THC content and no goods associated with smoking or other non-intoxicating cannabis applications. Health food stores or pharmacies offering hemp products are not subject to such age restrictions. It is therefore also a question of the milieu, with which the CBD products surround themselves, whether they are perceived as health-promoting or as questionable. Safety of CBD is confirmed by WHOAfter intensive research into the substance, the World Health Organization WHO has declared Cannabidiol safe to use. No adverse health effects or risks associated with the use of CBD could be identified during the studies carried out by the WHO itself. This means in plain language that you could not prove any side effects or the like. This makes CBD safer than most drugs that are available in the pharmacy over the counter. So who would give his child an ibuprofen in pain or aspirin, which should also be able to safely administer CBD, if the child has a condition that can be positively influenced by CBD. Is CBD suitable for children only as a remedy or as a nutritional supplement?The fact that CBD can help children suffering from epilepsy, for example, or other serious ailments has been proven by numerous studies and is now also relatively well-known through reports that have become public. However, many people may believe that they need to keep their CBD products away from their children. This is not the case, because CBD is also excellent for children for general health promotion. For example, if children are sleeping badly, or are suffering from anxiety, or are generally tormented by restlessness, cannabidiol can help them relax and sleep well. Even in children diagnosed with ADHD, CBD can be used effectively to prevent treatment with Ritalin. CBD can easily be integrated into a child's everyday life without the impression of medication. Many of the very natural products can be used to prepare drinks and food. Source: GLASMANN, Dieter Klaus. Ist CBD für Kinder geeignet? 1 [online] Dec, 2018, Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/cbd-in-der-medizin/ist-cbd-fuer-kinder-geeignet/ source photo: https://pixabay.com/cs/folder_openPřiřazené štítky

folder_openPřiřazené štítky

What is Cannabis Drug (CBC)?

access_time24.October 2019personEditor Testovací

Cannabis Cirrus (CBC) is one of over 100 cannabinoids. Although the phytocannabinoid itself has no analgesic effect, it is believed to play an important role in relieving pain and inflammation. Besides CBD and THC, cannabis is a less well-known cannabinoid. CBC is not psychoactive and it is believed that it can significantly enhance the effects of other cannabinoids. Thus, it could play an important role in the entourage effect. In 1966, science first became aware of CBC. Although the drug is not receiving much attention, the potential of CBC is quite promising. Researchers believe it plays a key role in the anti-inflammatory and analgesic effects of CBD and THC, and that CBCA is formed from the acid. How does CBC work?Like all other cannabinoids, CBC interacts with the CB1 and CB2 receptors of our endocannabinoid system. In addition, cannabis bromide also affects the receptors TRPA1 and TRPV1. These channels play a central role in signal transmission and the sensation of pain. CBC is considered to be one of the most abundant cannabinoids and is the third most common phytocannabinoid after THC and CBD - a strong argument for more intensive research into its potential. The meaning of CBCIn cannabis, the combined effect of individual cannabinoids, also referred to as the entourage effect, plays a crucial role. This means that cannabis chromosomes can make an important contribution to the effects of THC or CBD as well as other compounds. This is also the reason why patients with full-spectrum extracts have the best experience. It's not that there's no data on the medical potential of cannabis chromosomes at all. In 2016, the Journal for Experimental Dermatology published a study ) examining the efficacy of CBC and other non-psychoactive cannabinoids in the treatment of acne and other skin problems , The data collected suggest that CBC, CBDV and THCV may inhibit the onset of acne. In addition, all cannabinoids showed a promising anti-inflammatory effect. CBC In the 1970s, it was found that CBC was found mainly in Indian landrace varieties. By crossing and creating new varieties with a high THC content and altered genetic make-up, it may now be difficult to find plants of comparable value to those of the past. Analysis results of medical strains such as Bedrocan, which is issued in German pharmacies, show how small the proportion of CBC is still. In the case of Bedrocan, the analysis shows a level of 0.01-0.12% CBD. Source: BOEDEFELD, Christian. Was ist Cannabichromen (CBC)? 1 [online], 13 Nov, 2018 Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/was-ist-cannabichromen-cbc/ source photo: https://pixabay.com/cs/  

folder_openPřiřazené štítky

What are phytocannabinoids?

access_time24.October 2019personEditor Testovací

Phytocannabinoids are cannabinoids produced by plants. Mainly these agents are found in cannabis plants. However, there are also indications that phytocannabinoids are also formed by other plants. Just like endocannabinoids, they activate our cannabinoid receptors. The plant genus Cannabis Sativa contains more than 100 phytocannabinoids, which belong to the group of so-called terpephenols. The best-known phytocannabinoids include THC and CBD. This group of substances has not been discovered in any other plant. Phytocannabinoids activate the CB1 and CB2 receptors of the endocannabinoid system and thereby produce their characteristic effect. The active ingredients are agonists (that is, the occupation of a receptor activates a process) or antagonists (the activation inhibits a cell process) of the CB1 or CB2 receptors. Phytocannabinoids have a high potential for use as medicine. The counterpart to this are endogenous cannabinoids. They are produced by our bodies themselves and are involved in metabolic processes and other important tasks. The two most important endocannabinoids include anandamide, 2-arachidonylglycerol (2-AG). Our endogenous cannabinoid system consists of countless receptors distributed throughout our body. CB1 receptors are mainly found in the brain, while the immune system and central nervous system are mostly CB2 receptors. It is believed that our endocannabinoid system is responsible for maintaining the balance in the body and plays an important role in our well-being. The most important phytocannabinoidsTetrahydrocannabidiol (THC)THC is probably the best-known phytocannabinoid and provides the psychoactive effect of cannabis use. This is precisely the reason why cannabis is considered illegal in many parts of the world. It can affect mood and appetite and is known for its anti-inflammatory effects. Cannabidiol (CBD)At least as well known is CBD. Cannabidiol is valued above all for its therapeutic properties, which as a dietary supplement is an ideal enrichment to the daily diet. It is not psychoactive and is legally available in many countries in the form of oils or creams. Cannabigerol (CBG)CBG is considered the precursor of most other phytocannabinoids. The cannabinoid is thought to have a variety of therapeutic uses, with studies suggesting that it is even more effective than CBD in certain conditions. Over time, enzymes from the plant convert cannabigerol into other cannabinoids, which is why the level in the "finished" plant is relatively low. Cannabidivarin (CBDV)CBDV is another non-psychoactive cannabinoid. The chemical structure is very similar to CBD and the use of cannabidivarin in the treatment of epilepsy is currently under investigation. Cannabichromene (CBC)CBC is a cannabinoid that could be of interest for its medicinal properties. Studies give an idea of ​​how CBC produces antigens in tumor cells by activating CB2 receptors that are cleared by immune cells. In addition, the use of cannabichromene in Alzheimer's therapy is discussed. Of course, these are just a small selection of the most popular phytocannabinoids. Currently, more than 100 phytocannabinoids of the cannabis plant are known, which unfold their unique effect, the entourage effect. Phytocannabinoids play an important role in our endocannabinoid system. Although some progress has already been made in research, more efforts are needed to unlock the full potential of these compounds. Source: BOEDEFELD, Christian. Was sind Phytocannabinoide? 1 [online]. 8 Nov, 2018. Dostupné z: https://www.hanf-magazin.com/medizin/cannabinoide/was-sind-phytocannabinoide/ source photo: https://pixabay.com/cs/

folder_openPřiřazené štítky